https://www.selleckchem.com/pr....oducts/nutlin-3a.htm
Aim Roles of forced running exercise (FE) in remediation of neurogenesis inhibition and radiation-induced cognitive dysfunction were investigated in a whole-brain irradiation mice model via the regulation of DNA 5-hydroxymethylation modification (5 hmC) and its catalytic enzymes ten-eleven translocation (Tet) proteins. Materials methods Hippocampal neurogenesis and cognitive function, DNA 5 hmC level and Tet expression were determined in mice. Results The expression of DNA 5 hmC and Tet2, brain-derived neurotrophic factor signif
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