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CONCLUSIONS The microdosed FXaI cocktail approach is able to generate drug interaction data and can help elucidating the mechanism involved in the clearance of the different victim drugs. This is a safe approach to concurrently study drug-drug interactions with a drug class. (EudraCT 2016-003024-23). © 2020 The Authors. British Journal of Clinical Pharmacology published by John Wiley Sons Ltd on behalf of British Pharmacological Society.BACKGROUND An increasing number of publications on social media has paralleled the growth of