https://ch-223191antagonist.co....m/reduction-in-the-p
AML relapse may be due to leukemic stem cells (LSC). Particularly, the "cancer tumors stem mobile" theory, which relates to LSCs, is controversial and criticized as a result of technical peculiarities regarding the xenotransplant of individual cells into mice. In this study, we searched for possible LSCs in an immunocompetent synergetic mice model. Initially, we discovered phenotypic heterogeneity within the ML23 leukemia line. We prospectively isolated a sub-popu