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Over the last many years, we've established a rodent model of COPD-induced skeletal muscle disorder that allowed a disaggregated interrogation regarding the mobile and physiological results driven by COPD through the people unique to hypercapnia. We discovered that while COPD and hypercapnia synergistically subscribe to muscle atrophy, these are typically antagonistic procedures regarding fibers respiratory capacity. We propose that AMP-activated necessary protein kinase (AMPK) is an essential regula
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