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We designed a biodegradable hydrogel formulation made up of reasonable and hif the gels over time indicated that the thermosensitive solution because of the higher polymer focus increased more than 4-fold in size in vivo after 3 days, that has been significantly different from the inside vitro behavior where a volume change of 35% ended up being seen. Our study demonstrates the potential of MRI to noninvasively monitor in vivo intracerebral protein launch from a l