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5% subjects diagnosed with ADHD as primary diagnosis. Detection of CNVs of unknown clinical significance was similar in the two groups being 27% and 32% respectively. Benign and likely benign CNVs accounted for 61% and 59.5% in the first and second group respectively. Differences in the diagnostic yield were not statistically significant between the two groups (P 0.05). Our data strongly suggest that array-CGH (a) is a valuable diagnostic tool to detect clinically significant CNVs in individuals with ADHD even in the absence
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