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The ability to prevent number macrophage apoptosis is amongst the survival methods of intracellular bacteria, including Brucella. In the present study the role of Mg2+/Mn2+ dependent necessary protein phosphatase 1A (PPM1A) within the apoptosis of Brucella suis (B. suis) strain 2 vaccine-infected BV2 cells was investigated. Weighed against control cells, the protein appearance levels of cleaved caspase-3 had been markedly increased in PPM1A short hairpin (sh)RNA-transfected BV2 cells. Flow cytome
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