https://www.selleckchem.com/pr....oducts/FK-506-(Tacro
o.). Since DHA and OMP exhibited a protective effect in a dose-responsive fashion, the ED30 for each individual compound was determined and a 11 combination of DHA and OMP was tested. Isobolographic analysis was used to determine any pharmacodynamic interactions. Since the effective experimental dose ED30 (Zexp) of the combined treatment of DHA and OMP was lower than the theoretical additive dose (Zadd; p less then .05) in both the stomach and small intestine their protective effects were considered synergistic. These resul
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