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Chronic disease is a major concern with an aging population, and arthritis is one of the most prevalent chronic diseases affecting 10% of the population. Self-management can be appropriate to relieve the outcome of osteoarthritis as one of the most suitable approaches in people with chronic diseases. This study aimed to determine the effect of self-management education programs on the outcome of knee osteoarthritis in adult patients. Eighty participants were randomized into either control (4 or intervention (4 groups. Initially, dem