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Collectively, this study has linked the PTEN/AKT signaling axis to deregulated epigenetic changes in myeloid malignancies. It also provides a rationale for mechanism-based therapy for patients with ASXL1 mutations. © The Author(s) 2020. Published by Oxford University Press on behalf of Journal of Molecular Cell Biology, IBCB, SIBS, CAS.Colletotrichum species are the most important postharvest spoilage of papaya fruit. The objective of this research was to evaluate the effect of temperature and relative humidity on growth rate and time fo
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