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05). In vitro cytotoxicity studies on HaCat cells showed significantly higher cell viability than the pure drug solution (p  less then  0.05). The enhanced skin permeation and high cell viability associated with this formulation suggest a promising carrier for transdermal delivery. Gene-environment interactions contribute to schizophrenia aetiology. is a well-established genetic risk factor for schizophrenia, and elevated expression of type III neuregulin 1 mRNA in the dorsolateral prefrontal cortex is observed in patients with a core