https://www.selleckchem.com/pr....oducts/thapsigargin.
Graphic abstract.The organoiridium complex Ir[(C,N)2(O,O)] (1) where C, N = 1-phenylisoquinoline and O,O = 2,2,6,6-tetramethyl-3,5-heptanedionate is a promising photosensitiser for Photo-Dynamic Therapy (PDT). 1 is not toxic to cells in the dark. However, irradiation of the compound with one-photon blue or two-photon red light generates high levels of singlet oxygen (1O2) (in Zhang et al. Angew Chem Int Ed Engl 56 (47)14898-14902 https//doi.org/10.1002/anie.201709082,2017), both within cell monolayers and in tumour models. Moreover
Like
Comment
Share
