https://www.selleckchem.com/pr....oducts/pqr309-bimira
BACKGROUND GRIN-related developmental-epileptic encephalopathies are associated with a spectrum of neurodevelopmental disorders, including intellectual disability, epilepsy including continuous spike-and-wave during sleep syndrome (CSWS), or epilepsy-aphasia spectrum phenotypes such as in Landau-Kleffner syndrome. Efficacy of IVIG treatment was recently reported in a patient with LKS related to GRIN2A mutation. AIM AND METHODS We describe the efficacy of Immunotherapy in 5 consecutive patients (4 males, age range 6 months-13