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The 3D architectural analysis and practical forecast revealed that all these eight variants may impact AMPAR expression or purpose, and influence the synaptic plasticity by controlling the palmitoylation of PSD95 and AKAP79/150. CONCLUSION Our results first reveal powerful supporting evidences of this connection amongst the ZDHHC2 and SCZ, also provide a fine-mapping of variations of this gene in Han Chinese SCZ customers. © 2020 The Authors. Molecular Ge