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Inhaled Nitric oxide (iNO), possesses anti-viral properties, improves oxygenation, and was been shown to be safe in infants with breathing problems. Hospitalized infants with acute bronchiolitis had been therefore recruited to a prospective double-blinded, multi-center, randomized controlled pilot study. They obtained periodic large dosage iNO (160 ppm) plus oxygen/air for 30 min or oxygen/air alone (control), five times/day, as much as 5 times. Sixty-nine infants were enrolled. No differen