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https://www.selleckchem.com/products/SNS-032.html
Alzheimer's disease is a neurodegenerative disease in which the degree of cortical atrophy in specific structures of the brain serves as a useful imaging biomarker. Recent approaches using linear mixed effects (LME) models in longitudinal neuroimaging have been powerful and flexible in investigating the temporal trajectories of cortical thickness. However, massive-univariate analysis, a simplified approach that obtains a summary statistic (e.g., a p-value) for every vertex along the cortex, is insufficient to model cortical atrophy beca