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Within these structures, the base-labile protecting group 9-fluorenylmethyloxycarbonyl (Fmoc) had been paired into the p-toluensulfonyl (tosyl, Ts) or acid-labile tert-butyloxycarbonyl (Boc) moieties. The artificial method of protected l-Dap methyl esters utilizes accordingly masked 2,3-diaminopropanols, which are obtained via reductive amination of an aldehyde ready from the commercial amino acid Nα-Fmoc-O-tert-butyl-d-serine, used once the beginning material. Redu
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