https://www.selleckchem.com/pr....oducts/pf-3758309.ht
Ketamine has become a popular recreational drug due to its neuronal anesthesia effect and low price. The process of learning and memory is part of the distinctive high-level neural activities in animals. We investigated the effects of subanesthetic and anesthetic doses of ketamine on the learning and memory-related signal transduction mechanisms. We used the Morris water maze test to execute rats' learning and memory ability and detected changes of Arc mRNA and Arc, cAMP-response element-binding protein (CRE, phospho-CREB (p-CRE,
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