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https://www.selleckchem.com/pr....oducts/bay-11-7082-b
BACKGROUND Guzhi Zengsheng Zhitongwan (GZZSZTW) is an effective Chinese medicinal formulation for the treatment of osteoarthritis (OA) designed according to the "kidney governing bone" theory, which has been widely used as a golden guide for treating bone and cartilage diseases in traditional Chinese medicine. The aim of this study was to explore the molecular mechanism underlying its effects on the bone and kidney. METHODS Preparation and quality control were performed as previously described. Since GZZSZTW is orally ad