https://www.selleckchem.com/pr....oducts/solcitinib.ht
Long non-coding RNAs (lncRNAs) play critical roles in regulating the progression of cerebral ischemia. LncRNA H19 was significantly up-regulated under ischemia-reperfusion (I/R) damage and implicatedin I/R injury progression, but the mechanisms remain unclear. Mice were subjected to middle cerebral artery occlusion (MCAO)/R (1 h/24 h) to build an I/R injury model and the infarct volume and neurological deficit were assessed. Human neuroblastoma cell line SH-SY5Y was used in oxygen-glucose deprivation and reperfusion (OGD/R, 3 h/24 h)
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