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The outbreak of the coronavirus (Covid-19) pandemic has seriously impacted negatively on the socio-economic and political activities in the international system. The pandemic has exposed the leadership capacities and health investments cum preparedness of countries across the globe. This paper studies the reactions and responses of nations in containing the deadly virus and observes that while Western nations react rapidly and more proactively, African nations seem to be caught in a web of religious prevarications and State fragility