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https://azd4573inhibitor.com/a....ssessment-involving-
Although a lot of studies have reported the consequence of truncation on the aggregation of Tau, these researches mainly utilized extremely artificial circumstances, utilizing heparin sulfate or arachidonic acid to induce aggregation. Here, we report for the first time the pathological activities of varied truncations of Tau, including site-specific phosphorylation, self-aggregation, binding to hyperphosphorylated and oligomeric Tau isolated from advertisement brain structure (AD O-T