https://www.selleckchem.com/products/pf-8380.html
I-labeled m-iodobenzylguanidine ([ I]MIBG) has been used to treat neuroblastoma patients, but [ I]MIBG may be immediately excreted from the cancer cells by the adenosine triphosphate binding cassette transporters, similar to anticancer drugs. The purpose of this study was to clarify the efflux mechanism of [ I]MIBG in neuroblastomas and improve accumulation by inhibition of the transporter in neuroblastomas. [ I]MIBG was incubated in human embryonic kidney (HEK)293 cells expressing human organic anion transporting polypeptide (OATP)1B1,
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