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But, only ILC2s, not TH cells, revealed increased ST2 expression in the start of eosinophil development, which dramatically correlated with all the wide range of eosinophil progenitors. To sum up, our results suggest that airway allergen challenges with HDM activates IL-33-responsive ILC2s, TH cells, and eosinophils locally in the bone tissue marrow. Focusing on the IL-33/ST2 axis in allergic diseases including symptoms of asthma a very good idea by lowering eosinophil manufacturin