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and enhanced ketogenesis was identified in the ODS group.This trial was registered at clinicaltrials.gov as NCT01616082. Threshold serum 25-hydroxyvitamin D [25(OH)D] concentrations for extraskeletal outcomes are uncertain and could differ from recommendations (20-30 ng/mL) for skeletal health. We aimed to identify and validate sex-specific threshold 25(OH)D concentrations for older adults' physical function. Using 5 large prospective, population-based studies-Age, Gene/Environment Susceptibility-Reykjavik (n=4858, Iceland); Health, Agi