https://www.selleckchem.com/pr....oducts/Cyclopamine.h
In this review, we discuss the molecular mechanisms underlying hypoxia-induced aggressive and therapeutically resistant phenotypes in both pancreatic cancerous and stromal cells. Additionally, we focus more on innovative therapies targeting the tumor hypoxic microenvironment itself, which hold great potential to overcome the resistance to chemotherapy and radiotherapy and to enhance antitumor efficacy and reduce toxicity to normal tissues. The survival and proliferation of multiple myeloma (MM) cells in the bone marrow (BM) critical
Like
Comment
Share
