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Using this basic approach, which we refer to as tripartite constellation evaluation (TCA), we dedicated to large-diameter dorsal-root ganglion (L-DRG) neurons with myelinated axons. Divergent reactions to the K-channel antagonist, κM-conopeptide RIIIJ (RIIIJ), reliably identified six discrete practical cell courses. In two neuronal subclasses (L1 and L2), block with RIIIJ generated a rise in [Ca] i Simultaneous electrophysiology and calcium imaging revealed that the RIIIJ-elicited boo
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