https://www.selleckchem.com/products/U0126.html
Genetic and epigenetic mechanisms regulate antimicrobial immunity against (Mtb) infection. The present study assessed circular RNA TRAPPC6B (circTRAPPC6 for antimicrobial immune functions and defined mechanisms wherein circTRAPPC6B regulates Mtb growth, autophagy and microRNA in macrophages. The Mtb infection of monocytes/macrophages resulted in a significantly decreased level of circTRAPPC6B that inhibited intracellular Mtb growth in macrophages. Conversely, circTRAPPC6B expression enhanced autophagy or autophagy-associated protein LC3
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