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Our aim is that this review will provide a broad survey of the issues involved in fomite transmission and intervention to a wide range of readers to better enable them to take on the open research challenges.Low-dose computed tomography (LDCT) is desired due to prevalence and ionizing radiation of CT, but suffers elevated noise. To improve LDCT image quality, an image-domain denoising method based on cycle-consistent generative adversarial network ("CycleGAN" is developed and compared with two other variants, IdentityGAN and GAN-CIRCL