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Furthermore, 2962 differentially expressed genes (DEGs) were identified after Cry1Ca challenge, including 1508 up-regulated and 1454 down-regulated unigenes. Among these DEGs, cleansing (CYP, CarE, and GST) and Bt weight (ALP, APN, and ABC transporter)-related genetics had been differentially expressed into the midgut of S. exigua after Cry1Ca therapy. However, most DEGs of defensive enzymes had been down-regulated, while most DEGs related to serine protease and REPAT had