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05). In men, in addition to these two pollutants, PM10 exposure was positively associated with TSH level (p = 0.03). Age-stratified analysis showed stronger effects of NO2 and CO exposure in older than in younger adults. Exposure to these air pollutants was related to serum TSH and FT4 concentrations in people with overweight or obesity but not in those of normal weight. Conclusions This study provides the first evidence that air pollution exposure is linked to thyroid function in the general population and that this association may be