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The RFS rate did not differ significantly between the treatment groups in the same tumor-size group ([Formula see text]1cm group P = .636, 1-2cm group P = .16. For T1 tumors, RFS rate was not different between local excision and radical resection ([Formula see text]1cm group P = .452, 1-2cm group P = .70. Depth of invasion, a high Ki-67 index, and margin involvement were confirmed as independent risk factors for recurrence. Among patients treated with endoscopic removal, endoscopic biopsy was a significant factor for worse RFS (P .001), w
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