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The consequent delayed diagnosis limits access to surgical procedures and impacts on survival. After correction for tumour burden, however, the survival is not different from that of viral HCC, suggesting that NAFLD-HCC is not intrinsically a more aggressive malignancy. CONCLUSIONS A great deal of efforts is needed to improve the clinical outcome of NAFLD-HCC, especially in terms of prevention, surveillance protocols and identification of drug modifying the natural history of the underlying liver disease. The outcome of these efforts wil