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Compounds 10 (6,7-dimethoxy-2,3,4,11b-tetrahydro-1H-fluoreno[9,1-cd]azepine) and 12 (6,7-dimethoxy-2-methyl-2,3,4,11b-tetrahydro-1H-fluoreno[9,1-cd]azepine) have been identified as structurally novel, high affinity (Ki = 5 nM), selective 5-HT6 receptor ligands. © 2020 John Wiley Sons A/S.In the current issue of BJOG, Andolf and colleagues use a national register to investigate the association between placental bed disorders and later dementia (BJOG 2020 xxxx). The authors consider a number of placental bed disorders in relation