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Molecular imprinted solid-phase extraction is the technique that uses molecular imprinted polymer as the sorbent in solid phase extraction. Molecular imprinted solid-phase extraction is effective and efficient for the extraction process and cleaning as compared with solid phase extraction (SPE) without molecular imprinted polymer. The complexity of variables in molecular imprinted solid-phase extraction arise as problems in the analysis, therefore it is necessary to optimize the extraction conditions of molecular imprinted solid-phase e