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24 (95% CI = 1.21-1.28, P  less then  .001). In subgroup analyses performed according to age and sex, all crude and adjusted hazard ratios of herpes zoster were higher in the peptic ulcer disease group than in the control group (each P  less then  .05). In another subgroup analysis according to follow-up periods, the crude and adjusted hazard ratios of herpes zoster were higher in the peptic ulcer disease group than in the control group except for less then 1 year periods after the index dates (each P  less then  .001).The hazard ratios