https://www.selleckchem.com/pr....oducts/pha-848125.ht
The prognostic value and molecular landscape of human epidermal growth factor receptor 2 (HER2) low-expressing (HER2-L) metastatic colorectal cancer (mCRC) remain unclear. This study enrolled patients with mCRC who had undergone surgical resection of primary tumor. Using the specimen, we evaluated HER2 expression by immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). HER2 positivity was defined as follows HER2 positivity (HER2-Pos) as IHC 3+ or IHC 2+/FISH positive, HER2-L as IHC 2+/FISH negative or IHC 1+, and
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