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Adult ADHD and Comorbid Disorders Many people suffering from ADHD have comorbid conditions like major depression (Kessler and colleagues, 2006). Many patients who are depressed do not respond well to medications and may benefit from therapy. Treatments that are most effective in reducing the symptoms of ADHD appear to increase and balance levels of certain brain chemicals called neurotransmitters. The stimulants methylphenidate and amphetamine are frequently prescribed. Medicines A v
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