https://romidepsininhibitor.co....m/changes-in-side-st
Similarly, PPARγ activation attenuated standard PH and RVH and increased HUWE1 and miR-98 in SS lungs. In vitro, hemin treatment decreased PPARγ, HUWE1, and miR-98 amounts and increased p65 appearance, HPAEC monocyte adhesion, and proliferation. These derangements were attenuated by pharmacological PPARγ activation. Focusing on these signaling pathways can favorably modulate a spectrum of pathobiological responses in SCD-PH pathogenesis, showcasing unique therapeutic targets in SCD pu
Like
Comment
Share
