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Moreover, only one individual with three copies ofSMN1 carried the two polymorphisms of g.27134 TG and g.27706_27707delAT. Therefore, we provided precise genetic counseling for these SMA families after confirming the (2+ carriers. The association between the polymorphisms of g.27134TG and g.27706_27707delAT and Chinese (2+ carriers might be weak. Hence, it is necessary to find specific polymorphisms in the Chinese population to improve the detection rate of (2+ carriers.Bacteria with the smallest genome contain genes nece