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0%, and hexadecanoic acid methyl ester (16 13.0%. Conclusion The results showed that the fatty acid composition is rich in polyunsaturated fatty acids. The essential oils of G. laricina Schreb. were dominated by fatty acid derivatives and n-alkanes. We think the results obtained from this research will stimulate further research on the chemistry of Gypsophila species.Objectives The aim of the present investigation was to develop a solid dispersion of itraconazole (ITR) using sacrificial excipients like pregelatinized starch an