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On the other hand, the methods provided for estimating PMImin provide the forensic entomologist more tools to reach accurate and reliable estimates. Few data are currently available about SB5 in inflammatory bowel diseases (IBD). The aim of this study was to assess the effectiveness and safety of SB5 in a cohort of patients with IBD in stable remission switched from the adalimumab (ADA) originator and in a cohort of patients with IBD naïve to ADA. We prospectively enrolled patients with IBD who started ADA treatment with SB5 (naïve cohort)