https://www.selleckchem.com/pr....oducts/Staurosporine
Results Our integrative analysis discovered LCAL62 as the most down-regulated lncRNA in metastasis. Further low LCAL62 expression promoted aggressive phenotypes and regulated genes associated with metastasis (such as metastasis repressor FOXA2). Low LCAL62 expression corresponded to poor overall patient survival across five independent lung adenocarcinoma cohorts (n = 881) including our own nanoString validation cohort. Conclusion We discovered that LCAL62 was down-regulated in lung cancer progression to promote invasive phenotype
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