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Adult ADHD and Comorbid Disorders Many people with ADHD also have comorbid disorders such as major depression (Kessler and colleagues, 2006). Many people who suffer from depression are not able to respond well to medications and may be able to benefit from therapy. Neurotransmitters are brain chemicals that regulate and boost levels of certain brain chemicals. Commonly prescribed stimulants include methylphenidate, amphetamine and other similar medications. Medications Adults can take a variety of