https://www.selleckchem.com/pr....oducts/Cladribine.ht
43±3.75nM and 3383±81.73 CPM, respectively. In cell uptake and blocking experiments, a significant reduction in radioactivity accumulation (over 4-fold) was observed by blocking U87 and PC-3 cells with unlabeled peptide. PET imaging of U87 and PC-3 tumor-bearing mice revealed clear tumor imaging (tumor radioactivity accumulation was 3.48±0.44 and 3.68±0.76%ID/g respectively, tumor-to-muscle ratio was 3.45±0.43 and 3.64±0.76 respectively). Blocking imaging revealed that the U87 tumor uptake was significantly inhibited (2.21±0.41%ID/g)