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 Plasma sTM levels were readily available for 263 customers with a significant bleed and 538 control subjects. sTM amounts were dose-dependently involving risk of major bleeding, with a 1.9-fold increased risk (95% CI 1.1-3.1) for levels over the 85th percentile versus the 25th percentile. A higher INR (≥4) when you look at the existence of high (≥70th percentile) sTM levels was associated with a 7.1-fold (95% CI 4.1-12.3) in