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Interleukins were only measured at admission, and were tested in serum, not in the cerebrospinal fluid. CONCLUSIONS Our study demonstrated that higher serum IL-8 levels may predict more severe withdrawal symptoms at 2 weeks after METH abstinence. © 2020 John Wiley Sons Ltd.OBJECTIVE The serum kynurenine pathway metabolites kynurenic acid (KYNA), kynurenine (KYN), and tryptophan (TRP) were examined in chronic ketamine users and in schizophrenic patients. The correlations of the metabolites with sociodemographic data, clinical charac