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We previously elucidated the protective mechanism of Korean red ginseng oil (RGO) against infection, and our phytochemical analysis revealed that palmitic acid (PA) was an abundant component of RGO. Consequently, we investigated the contribution of PA against . We aimed to investigate the efficacy of PA against infection using a murine cell line and a murine model. Cell viability, bactericidal, internalization, and intracellular replication, western blot, nitric oxide (NO), and superoxide (O₂⁻) analyses and flow cytometry were performed