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https://www.selleckchem.com/pr....oducts/hpk1-in-2.htm
ATP release was significantly higher with CX-4945, especially at high concentrations, as well as with TMZ/CX-4945. combined treatment may produce the simultaneous release of two potent immunogenic signals, which can explain the outperformance over single treatments in vivo. A word of caution may be raised since in vitro conditions are not able to mimic pharmacokinetics observed in vivo fully. combined treatment may produce the simultaneous release of two potent immunogenic signals, which can explain the outperformance over single trea