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Our work showed that MOOs treatment is capable of restoring GLUT3 level to improve depressive-like behaviors in PSD rats. We also propose GLUT3 as a potential therapeutic target for PSD and emphasize the importance of metabolism disturbance in PSD pathology. To address the physician workforce challenges in Thailand using Agent-Based Modeling (ABM). Physician planning and allocating have been modeled with the life cycle framework starting from medical school intakes, residency training, and career retirement. This study proposes a system